Opioid dependence syndrome (ODS) is a chronic relapsing remitting condition associated with Rebate significant impairment and mortality risk.Opioid substitution therapy is used worldwide, but long-term retention rates are low and there is risk of misuse and diversion.Yoga practice can improve quality of life, reduce chronic pain, and enhance endoge
Susceptibility and infectiousness of SARS-CoV-2 in children versus adults, by variant (wild-type, alpha, delta): A systematic review and meta-analysis of household contact studies.
ImportanceUnderstanding the susceptibility and infectiousness of children and adolescents in comparison to adults is important to appreciate their role in the COVID-19 pandemic.ObjectiveTo determine SARS-CoV-2 susceptibility and infectiousness of children and adolescents with adults as comparator for three variants (wild-type, alpha, delta) in the
Swimming Behavior of Daphnia magna Is Altered by Pesticides of Concern, as Components of Agricultural Surface Water and in Acute Exposures
Pesticides with novel modes of action including neonicotinoids and anthranilic diamides are increasingly detected in global surface waters.Little is known about how these pesticides of concern interact in mixtures at environmentally relevant concentrations, a common exposure scenario in waterways impacted by pesticide pollution.We examined effects
Treatment with MDL 72527 Ameliorated Clinical Symptoms, Retinal Ganglion Cell Loss, Optic Nerve Inflammation, and Improved Visual Acuity in an Experimental Model of Multiple Sclerosis
Multiple Sclerosis (MS) is a highly disabling neurological disease characterized by inflammation, neuronal damage, and demyelination.Vision impairment is one of the color depositing mask major clinical features of MS.Previous studies from our lab have shown that MDL 72527, a pharmacological inhibitor of spermine oxidase (SMOX), is protective agains
Bazam: a rapid method for read extraction and realignment of high-throughput sequencing data
Abstract The vast quantities of short-read sequencing data being generated are often exchanged and stored as aligned reads.However, aligned data becomes outdated Tweezer as new reference genomes and alignment methods become available.Here we describe Bazam, a tool that efficiently extracts the original paired FASTQ from alignment files (BAM or CRAM